Could a stroke drug help dementia patients?
NCT ID NCT03804229
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This Phase 3 trial tests whether butylphthalide soft capsules can improve thinking, memory, and daily living skills in people with mild to moderate vascular dementia. About 707 participants are randomly assigned to receive either the drug or a placebo for 52 weeks. The study aims to confirm earlier promising results from a Phase 2 trial.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Butylphthalide soft capsule
What this could lead to
If successful, this could provide a new treatment option to slow cognitive decline and improve daily function in people with vascular dementia.
What could go wrong
This is a Phase 3 trial, but results are not yet published. The drug may not show significant benefit over placebo, and side effects are possible.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Xuanwu Hospital of Capital Medical University
Beijing, Beijing Municipality, 100053, China