Could pepcid and a skin lotion finally stop burn scar itching?

NCT ID NCT06801626

Recruiting now Symptom relief Sponsor: The University of Texas Medical Branch, Galveston Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a combination of famotidine (Pepcid) pills and cromolyn sodium lotion can reduce itching from burn scars. 44 adults with itchy burn scars will take either the active combo or a placebo (plus a standard antihistamine) for 6 months. The main goal is to see if itch severity drops, measured by a simple 0-10 scale.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Famotidine (Pepcid) and 4% cromolyn sodium lotion
What this could lead to: If it works, this could offer a new, effective way to reduce chronic itching from burn scars, improving quality of life.
What could go wrong: This is a small Phase 3 trial (44 people) and results may not apply to everyone. Itching is subjective, and the placebo group also gets an active antihistamine, so the added benefit of the study drugs may be modest.

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Conditions

The condition(s) this trial relates to.

burn injury Pruritus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BURN SCAR ITCH SCARRING WOUND

Contacts and locations

Locations

University of Texas Medical Branch, Galveston
RECRUITING

Galveston, Texas, 77555, United States

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