New injection may help knee replacement patients walk sooner

NCT ID NCT07616102

Not yet recruiting Symptom relief Sponsor: General Hospital of Ningxia Medical University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a single injection of bupivacaine liposome into the adductor canal can preserve leg muscle strength after total knee replacement, compared to a continuous nerve block with a catheter. Eighty patients aged 60-75 will be randomly assigned to one of the two nerve block methods. The main goal is to measure quadriceps strength using a handheld device, with the hope that the single injection leads to faster recovery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: bupivacaine liposome
What this could lead to: If it works, this could offer a way to recover leg strength faster after knee replacement surgery, helping patients walk sooner.
What could go wrong: This is a small, early-stage trial with only 80 participants, so results may not apply to everyone. The nerve block might not improve strength as hoped, and there are always risks with injections near nerves.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MUSCLE STRENGTH TKA

Contacts and locations

Locations

General hospital of Ningxia medical university

Yinchuan, Ningxia, China

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