New hope for rare lymphoma: targeted drug shows promise in small trial

NCT ID NCT05442554

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This completed Phase 4 trial tested the drug brentuximab vedotin in 10 Chinese adults with a rare type of skin lymphoma called CD30-positive cutaneous T-cell lymphoma. The goal was to see if the drug could shrink or eliminate cancer for at least 4 months and to check for long-term side effects. Participants received the drug through a vein every 3 weeks for up to 16 cycles.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

brentuximab vedotin (a drug given through a vein)

What this could lead to

If it works, this could offer a treatment option for Chinese patients with this rare lymphoma that targets cancer cells directly.

What could go wrong

This is a small, completed Phase 4 study with only 10 participants, so results may not apply broadly. Side effects from the drug are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

mycosis fungoides primary cutaneous anaplastic large cell lymphoma primary cutaneous CD30+ T-cell lymphoproliferative disease T-cell non-Hodgkin lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Huashan Hospital, Fudan University

    Shanghai, Shanghai Municipality, 200040, China

  • Peking University First Hospital

    Beijing, Beijing Municipality, 100034, China

  • Peking University Third Hospital

    Beijing, Beijing Municipality, 100191, China

  • West China Hospital, Sichuan University

    Chengdu, Sichuan, 610041, China