Promising new combo for childhood hodgkin lymphoma shows high remission rates

NCT ID NCT02979522

Ongoing Disease control Sponsor: Takeda Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a new drug combination (brentuximab vedotin plus standard chemotherapy) in 59 children with advanced, newly diagnosed Hodgkin lymphoma. The goal was to find the safest dose and see how well it shrinks tumors. Early results show many children achieved complete remission, but long-term disease control and possible side effects are still being monitored.

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Conditions

The condition(s) this trial relates to.

classic Hodgkin lymphoma Hodgkins lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HODGKIN DISEASE

Contacts and locations

Locations

Azienda Ospedaliera Citta della Salute e della Scienza di Torino

Torino, 10126, Italy
Azienda Ospedaliero Universitaria Ospedale Pediatrico Meyer

Florence, 50139, Italy
Children's Hospital Colorado

Aurora, Colorado, 80045, United States
Cincinnati Children's Hospital Medical Center

Cincinnati, Ohio, 45229, United States
Fondazione IRCCS Policlinico San Matteo

Pavia, 27100, Italy
GRAACC - Grupo de Apoio ao Adolescente e a Crianca com Cancer

São Paulo, 04023-062, Brazil
Hospital Santa Marcelina

São Paulo, 08270-070, Brazil
Hospital Sao Rafael S/A

Salvador, Estado de Bahia, 41253-190, Brazil
ICr - Instituto da Crianca - HCFMUSP

São Paulo, 05403-000, Brazil
INCA - Instituto Nacional de Cancer

Rio de Janeiro, 20230-230, Brazil
Jardim das Americas

Paranã, 81520-060, Brazil
NHO Nagoya Medical Center

Nagoya, Aichi-ken, 460-0001, Japan
Ospedale Pediatrico Bambino Gesu,UOC Onco-ematologia

Roma, 165, Italy
St. Marianna University School of Medicine Hospital

Kawasaki-shi, Kanagawa, 216-8511, Japan

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