Promising new combo for childhood hodgkin lymphoma shows high remission rates

NCT ID NCT02979522

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a new drug combination (brentuximab vedotin plus standard chemotherapy) in 59 children with advanced, newly diagnosed Hodgkin lymphoma. The goal was to find the safest dose and see how well it shrinks tumors. Early results show many children achieved complete remission, but long-term disease control and possible side effects are still being monitored.

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Conditions

The condition(s) this trial relates to.

classic Hodgkin lymphoma Hodgkins lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Azienda Ospedaliera Citta della Salute e della Scienza di Torino

    Torino, 10126, Italy

  • Azienda Ospedaliero Universitaria Ospedale Pediatrico Meyer

    Florence, 50139, Italy

  • Children's Hospital Colorado

    Aurora, Colorado, 80045, United States

  • Cincinnati Children's Hospital Medical Center

    Cincinnati, Ohio, 45229, United States

  • Fondazione IRCCS Policlinico San Matteo

    Pavia, 27100, Italy

  • GRAACC - Grupo de Apoio ao Adolescente e a Crianca com Cancer

    São Paulo, 04023-062, Brazil

  • Hospital Santa Marcelina

    São Paulo, 08270-070, Brazil

  • Hospital Sao Rafael S/A

    Salvador, Estado de Bahia, 41253-190, Brazil

  • ICr - Instituto da Crianca - HCFMUSP

    São Paulo, 05403-000, Brazil

  • INCA - Instituto Nacional de Cancer

    Rio de Janeiro, 20230-230, Brazil

  • Jardim das Americas

    Paranã, 81520-060, Brazil

  • NHO Nagoya Medical Center

    Nagoya, Aichi-ken, 460-0001, Japan

  • Ospedale Pediatrico Bambino Gesu,UOC Onco-ematologia

    Roma, 165, Italy

  • St. Marianna University School of Medicine Hospital

    Kawasaki-shi, Kanagawa, 216-8511, Japan