Breathe away the pain: new study tests Drug-Free injection relief
NCT ID NCT07172984
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether controlled breathing exercises can control pain during joint injections as well as local anesthesia. 136 participants will be randomly assigned to either receive lidocaine (standard care) or practice 5-minute breathing cycles. The goal is to see if the breathing group feels no more pain than the anesthesia group, potentially offering a needle-free, drug-free alternative.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- breathing exercises (cardiac coherence technique)
- What this could lead to
- If it works, this could offer a drug-free way to manage pain during joint injections, reducing reliance on local anesthetics.
- What could go wrong
- This is a small, early-stage trial (136 people). Breathing may not work as well as anesthesia for everyone, and results may not apply to other procedures.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 136 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Sep 2025
- Expected to finish
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Sep 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patient scheduled to undergo therapeutic ultrasound-guided joint or periarticular injection. * Patient able to sign an informed consent form to participate in the study Exclusion Criteria: * Patient able to sign an informed consent form to participate in the study - - Allergy to the injection product or anesthetic. * Injection not allowing the use of a local anesthetic due to insufficient joint volume (e.g., fingers/toes). * Epidural injection via the sacrococcygeal hiatus. * Pregnant women
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Centre Hospitalier Métropole Savoie
RECRUITINGChambéry, 73000, France
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