Breath test could revolutionize lung cancer screening

NCT ID NCT06016569

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study is testing whether a breath test can detect lung cancer early in people at high risk. Researchers will collect breath samples from 3,200 current or former smokers aged 55-74 and compare the results to standard low-dose CT scans. If the breath test works well, it could offer a cheaper, easier way to screen for lung cancer.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

What this could lead to
If successful, this could provide a simple, low-cost breath test to screen for lung cancer, potentially reducing unnecessary procedures and deaths.
What could go wrong
This is an early validation study, not a treatment trial. The breath test may not be accurate enough to replace CT scans, and results may not apply to all populations.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • General University Hospital in Prague

    NOT_YET_RECRUITING

    Prague, 12808, Czechia

  • Masaryk Memorial Cancer Institute

    RECRUITING

    Brno, 65653, Czechia

  • University Hospital

    NOT_YET_RECRUITING

    Olomouc, 77900, Czechia

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