Breastfeeding's hidden effect on heart health in moms with genetic high cholesterol

NCT ID NCT05367310

First seen Feb 05, 2026 · Last updated May 15, 2026 · Updated 14 times

Summary

This study looks at how breastfeeding changes cholesterol and heart disease risk in women with familial hypercholesterolemia (FH), a genetic condition causing very high cholesterol. Researchers will follow 50 pregnant women (with and without FH) from late pregnancy through one year after giving birth, collecting blood and breast milk samples. The goal is to understand if breastfeeding affects heart risk differently in women with FH, and to measure how much cholesterol-lowering medication passes into breast milk.

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Contacts and locations

Locations

  • Centre of Cardiovascular Surgery and Transplantation

    Brno, Czechia

  • Department of Internal Medicine, Erasmus MC Cardiovascular Institute

    Rotterdam, Netherlands

  • Oslo University Hospital

    Oslo, Norway

  • Third Department of Internal Medicine, General University Hospital, First Faculty of Medicine, Charles University

    Prague, Czechia

Conditions

Explore the condition pages connected to this study.