New study aims to spare healthy breast tissue during cancer surgery

NCT ID NCT05825482

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study compares two surgical approaches for breast cancer: one that removes extra tissue around the tumor (routine cavity shave margins) and one that uses a special device (Savi Scout®) to guide removal of only suspicious margins. About 204 women with early-stage breast cancer will take part. The goal is to see which method better ensures all cancer is removed while removing less healthy tissue, potentially lowering the need for repeat surgeries.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Savi Scout® localization device

What this could lead to

If successful, this could help surgeons remove breast cancer more precisely, reducing the need for additional surgeries and preserving more healthy breast tissue.

What could go wrong

This is a relatively small, early-stage study (204 participants) comparing surgical techniques, not testing a new drug. Results may not apply to all breast cancer types or hospitals.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm ductal breast carcinoma in situ invasive breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cleveland Clinic Akron General, Case Comprehensive Cancer Center

    RECRUITING

    Akron, Ohio, 44302, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••