New combo drug trial aims to stall advanced breast cancer

NCT ID NCT05963984

Summary

This study tested whether adding an experimental drug called samuraciclib to the standard hormone therapy fulvestrant could better control advanced breast cancer that has stopped responding to prior treatments. It involved 60 adults with hormone receptor-positive, HER2-negative breast cancer that had spread or was locally advanced. Participants were randomly assigned to receive either the combination or fulvestrant alone to compare safety and how well the cancer was controlled.

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Contacts and locations

Locations

  • Actualidad Basada en la Investigación del Cáncer

    Guadalajara, Jalisco, 44280, Mexico

  • Centro de Investigacion Clinica de Oaxaca

    Oaxaca City, 68020, Mexico

  • Cryptex Investigación Clínica S.A. de C.V.

    Cuauhtémoc, 06100, Mexico

  • Dr. Abdurrahman Yurtaslan Ankara Onkoloji Egitim ve Arastırma Hastanesi

    Ankara, 06200, Turkey (Türkiye)

  • Gazi University

    Ankara, 06120, Turkey (Türkiye)

  • Gulhane Egitim ve Arastirma Hastanesi

    Ankara, 06010, Turkey (Türkiye)

  • Hacettepe Universite Hastaneleri

    Ankara, 06230, Turkey (Türkiye)

  • Hospital Clinico San Carlos

    Madrid, Madrid, Comunidad de, 28040, Spain

  • Hospital Clinico de Valencia

    Valencia, 46010, Spain

  • Hospital Infanta Cristina

    Badajoz, 06080, Spain

  • Hospital Universitari Vall d'Hebron

    Barcelona, 08035, Spain

  • Hospital Universitario Marqués de Valdecilla

    Santander, Cantabria Comunidad de, 39002, Spain

  • Hospital Universitario de Salamanca - Complejo Asistencial Universitario de Salamanca

    Salamanca, 37007, Spain

  • Hospital Vithas Málaga

    Málaga, 29016, Spain

  • I.E.U. Medical Point Hastanesi

    Izmir, 35575, Turkey (Türkiye)

  • Institut Català d'Oncologia - L'Hospitalet

    L'Hospitalet de Llobregat, Barcelona, 08908, Spain

  • Istanbul Universitesi Istanbul Tıp Fakultesi Hastanesi

    Istanbul, 34093, Turkey (Türkiye)

  • MD Anderson Cancer Center

    Madrid, 28015, Spain

  • Mfsmc-Hjwci

    Baltimore, Maryland, 21237, United States

  • Nograd Varmegyei Szent Lazar Korhaz

    Salgótarján, Nógrád megye, 3100, Hungary

  • Oaxaca Site Management Organization S.C.

    Oaxaca City, 68000, Mexico

  • Ocala Oncology Center PL DBA Florida Cancer Affiliates

    Ocala, Florida, 34474, United States

  • Parc de Salut Mar - Hospital del Mar

    Barcelona, 08003, Spain

  • Renati Innovation S.A.P.I de C.V

    Guadalajara, Jalisco, 44680, Mexico

  • Saint Luke's Cancer Institute

    Kansas City, Missouri, 64111, United States

  • Semmelweis Egyetem

    Budapest, 1082, Hungary

  • Sidney Kimmel Cancer Center - Jefferson Health

    Philadelphia, Pennsylvania, 19107, United States

  • Soltmed SMO

    Mexico City, Mexico City, 03650, Mexico

  • Szent Borbala Korhaz

    Tatabánya, Komárom-Esztergom, 2800, Hungary

  • TC Saglik Bakanligi Goztepe Prof. Dr. Suleyman Yalcin Sehir Hastanesi

    Istanbul, 34722, Turkey (Türkiye)

  • The Center for Cancer and Blood Disorders

    Fort Worth, Texas, 76104, United States

  • Trakya University

    Edirne, 22030, Turkey (Türkiye)

Conditions

Explore the condition pages connected to this study.