Trial halted early: targeted combo tested for tough breast cancer

NCT ID NCT04108858

Summary

This study aimed to see if adding a new drug called copanlisib to standard treatments could better control advanced HER2-positive breast cancer in people with specific genetic changes. It was designed to first find a safe dose and then test if the three-drug combination could keep the cancer from growing longer than the standard two-drug treatment. The trial was terminated early after enrolling only two participants.

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Contacts and locations

Locations

  • Los Angeles County-USC Medical Center

    Los Angeles, California, 90033, United States

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

  • UCHealth University of Colorado Hospital

    Aurora, Colorado, 80045, United States

  • USC / Norris Comprehensive Cancer Center

    Los Angeles, California, 90033, United States

  • University of Oklahoma Health Sciences Center

    Oklahoma City, Oklahoma, 73104, United States

Conditions

Explore the condition pages connected to this study.