Zapping spots: can targeted treatment stop spread of advanced breast cancer?

NCT ID NCT02364557

Completed Disease control Sponsor: NRG Oncology Source: ClinicalTrials.gov ↗

Summary

This trial tested if adding a precise, high-dose radiation treatment (called SBRT) or surgery to remove tumors, on top of standard drug therapy, could better control breast cancer that had spread to only one or two other places in the body. It involved 129 patients with this 'oligometastatic' stage of breast cancer. The goal was to see if aggressively treating these few spread-out spots could help patients live longer without their cancer getting worse.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Allegheny General Hospital

Pittsburgh, Pennsylvania, 15212, United States
Alta Bates Summit Medical Center-Herrick Campus

Berkeley, California, 94704, United States
Arizona Center for Cancer Care-Peoria

Peoria, Arizona, 85381, United States
Ascension Saint Vincent Anderson

Anderson, Indiana, 46016, United States
Ascension Via Christi Hospitals Wichita

Wichita, Kansas, 67214, United States
Banner University Medical Center - Tucson

Tucson, Arizona, 85719, United States
Benefis Healthcare- Sletten Cancer Institute

Great Falls, Montana, 59405, United States
Bon Secours Saint Mary's Hospital

Richmond, Virginia, 23226, United States
CHUM - Centre Hospitalier de l'Universite de Montreal

Montreal, Quebec, H2X 3E4, Canada
CHUM - Hopital Notre-Dame

Montreal, Quebec, H2L 4M1, Canada
CTCA at Southeastern Regional Medical Center

Newnan, Georgia, 30265, United States
CTCA at Western Regional Medical Center

Goodyear, Arizona, 85338, United States
Carle Cancer Center

Urbana, Illinois, 61801, United States
Case Western Reserve University

Cleveland, Ohio, 44106, United States
Cedars Sinai Medical Center

Los Angeles, California, 90048, United States
Central Maryland Radiation Oncology in Howard County

Columbia, Maryland, 21044, United States
Christus Saint Vincent Regional Cancer Center

Santa Fe, New Mexico, 87505, United States
Cleveland Clinic Akron General

Akron, Ohio, 44307, United States
Community Medical Center

Toms River, New Jersey, 08755, United States
Cross Cancer Institute

Edmonton, Alberta, T6G 1Z2, Canada
Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center

Lebanon, New Hampshire, 03756, United States
Decatur Memorial Hospital

Decatur, Illinois, 62526, United States
Diagnostic and Treatment Center

Weston, Wisconsin, 54476, United States
Dickstein Cancer Treatment Center

White Plains, New York, 10601, United States
Duke University Medical Center

Durham, North Carolina, 27710, United States
Edwards Comprehensive Cancer Center

Huntington, West Virginia, 25701, United States
Emory Saint Joseph's Hospital

Atlanta, Georgia, 30342, United States
Emory University Hospital Midtown

Atlanta, Georgia, 30308, United States
Emory University Hospital/Winship Cancer Institute

Atlanta, Georgia, 30322, United States
Froedtert West Bend Hospital/Kraemer Cancer Center

West Bend, Wisconsin, 53095, United States
Gene Upshaw Memorial Tahoe Forest Cancer Center

Truckee, California, 96161, United States
GenesisCare USA - Troy

Troy, Michigan, 48098, United States
Gibbs Cancer Center-Pelham

Greer, South Carolina, 29651, United States
Greater Baltimore Medical Center

Baltimore, Maryland, 21204, United States
Gundersen Lutheran Medical Center

La Crosse, Wisconsin, 54601, United States
Guthrie Medical Group PC-Robert Packer Hospital

Sayre, Pennsylvania, 18840, United States
Helen F Graham Cancer Center

Newark, Delaware, 19713, United States
Henry Ford Cancer Institute-Downriver

Brownstown, Michigan, 48183, United States
Henry Ford Hospital

Detroit, Michigan, 48202, United States
Henry Ford Macomb Hospital-Clinton Township

Clinton Township, Michigan, 48038, United States
Henry Ford West Bloomfield Hospital

West Bloomfield, Michigan, 48322, United States
Huntsman Cancer Institute/University of Utah

Salt Lake City, Utah, 84112, United States
IU Health Ball Memorial Hospital

Muncie, Indiana, 47303, United States
Inova Fairfax Hospital

Falls Church, Virginia, 22042, United States
Jewish General Hospital

Montreal, Quebec, H3T 1E2, Canada
John B Amos Cancer Center

Columbus, Georgia, 31904, United States
Kaiser Permanente Cancer Treatment Center

South San Francisco, California, 94080, United States
Kalispell Regional Medical Center

Kalispell, Montana, 59901, United States
King Faisal Specialist Hospital and Research Centre

Riyadh, 11211, Saudi Arabia
Lahey Hospital and Medical Center

Burlington, Massachusetts, 01805, United States
Legacy Good Samaritan Hospital and Medical Center

Portland, Oregon, 97210, United States
Legacy Mount Hood Medical Center

Gresham, Oregon, 97030, United States
Legacy Salmon Creek Hospital

Vancouver, Washington, 98686, United States
Lewis Hall Singletary Oncology Center

Thomasville, Georgia, 31792, United States
London Regional Cancer Program

London, Ontario, N6A 4L6, Canada
Los Angeles General Medical Center

Los Angeles, California, 90033, United States
Lovelace Medical Center-Saint Joseph Square

Albuquerque, New Mexico, 87102, United States
Lovelace Radiation Oncology

Albuquerque, New Mexico, 87109, United States
Lowell General Hospital

Lowell, Massachusetts, 01854, United States
Loyola University Medical Center

Maywood, Illinois, 60153, United States
M D Anderson Cancer Center

Houston, Texas, 77030, United States
Maine Medical Center- Scarborough Campus

Scarborough, Maine, 04074, United States
Maine Medical Center-Bramhall Campus

Portland, Maine, 04102, United States
MaineHealth Cancer Care Center of York County

Sanford, Maine, 04073, United States
MaineHealth Coastal Cancer Treatment Center

Bath, Maine, 04530, United States
MaineHealth/SMHC Cancer Care and Blood Disorders-Biddeford

Biddeford, Maine, 04005, United States
MaineHealth/SMHC Cancer Care and Blood Disorders-Sanford

Sanford, Maine, 04073, United States
Marshfield Medical Center-River Region at Stevens Point

Stevens Point, Wisconsin, 54482, United States
Mayo Clinic in Florida

Jacksonville, Florida, 32224-9980, United States
Mayo Clinic in Rochester

Rochester, Minnesota, 55905, United States
McGill University Department of Oncology

Montreal, Quebec, H2W 1S6, Canada
McKee Medical Center

Loveland, Colorado, 80539, United States
Medical College of Wisconsin

Milwaukee, Wisconsin, 53226, United States
Memorial Hospital West

Pembroke Pines, Florida, 33028, United States
Memorial Hospital of South Bend

South Bend, Indiana, 46601, United States
Memorial Medical Center

Springfield, Illinois, 62781, United States
Memorial Regional Hospital/Joe DiMaggio Children's Hospital

Hollywood, Florida, 33021, United States
Mercy Hospital

Coon Rapids, Minnesota, 55433, United States
Mercy Hospital South

St Louis, Missouri, 63128, United States
Methodist Medical Center of Illinois

Peoria, Illinois, 61636, United States
Miami Cancer Institute

Miami, Florida, 33176, United States
Michigan Healthcare Professionals Clarkston

Clarkston, Michigan, 48346, United States
Michigan Healthcare Professionals Farmington

Farmington Hills, Michigan, 48334, United States
Midwestern Regional Medical Center

Zion, Illinois, 60099, United States
Missouri Baptist Medical Center

St Louis, Missouri, 63131, United States
Montefiore Medical Center - Moses Campus

The Bronx, New York, 10467, United States
NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center

New York, New York, 10032, United States
Naval Medical Center -San Diego

San Diego, California, 92134, United States
New Mexico Oncology Hematology Consultants

Albuquerque, New Mexico, 87109, United States
Northwestern Medicine Cancer Center Delnor

Geneva, Illinois, 60134, United States
Northwestern Medicine Cancer Center Warrenville

Warrenville, Illinois, 60555, United States
Northwestern University

Chicago, Illinois, 60611, United States
Novant Cancer Institute Radiation Oncology - Supply

Supply, North Carolina, 28462, United States
Novant Health Cancer Institute Radiation Oncology - Wilmington

Wilmington, North Carolina, 28401, United States
Novant Health New Hanover Regional Medical Center

Wilmington, North Carolina, 28401, United States
Ogden Regional Medical Center

Ogden, Utah, 84405, United States
Ohio State University Comprehensive Cancer Center

Columbus, Ohio, 43210, United States
Orlando Health Cancer Institute

Orlando, Florida, 32806, United States
Ottawa Hospital and Cancer Center-General Campus

Ottawa, Ontario, K1H 8L6, Canada
Owensboro Health Mitchell Memorial Cancer Center

Owensboro, Kentucky, 42303, United States
Parkview Hospital Randallia

Fort Wayne, Indiana, 46805, United States
Parkview Regional Medical Center

Fort Wayne, Indiana, 46845, United States
Penrose-Saint Francis Healthcare

Colorado Springs, Colorado, 80907, United States
Piedmont Hospital

Atlanta, Georgia, 30309, United States
Poudre Valley Hospital

Fort Collins, Colorado, 80524, United States
ProMedica Flower Hospital

Sylvania, Ohio, 43560, United States
Providence Portland Medical Center

Portland, Oregon, 97213, United States
Providence Saint Vincent Medical Center

Portland, Oregon, 97225, United States
Queen's Medical Center

Honolulu, Hawaii, 96813, United States
Reading Hospital

West Reading, Pennsylvania, 19611, United States
Regions Hospital

Saint Paul, Minnesota, 55101, United States
Renown Regional Medical Center

Reno, Nevada, 89502, United States
Rex Hematology Oncology Associates-Blue Ridge

Raleigh, North Carolina, 27607, United States
Rex Hematology Oncology Associates-Cary

Cary, North Carolina, 27518, United States
Rex Hematology Oncology Associates-Garner

Garner, North Carolina, 27529, United States
Rush University Medical Center

Chicago, Illinois, 60612, United States
Saint Francis Medical Center

Cape Girardeau, Missouri, 63703, United States
Saint Joseph Mercy Oakland

Pontiac, Michigan, 48341, United States
Saint Joseph's Medical Center

Stockton, California, 95204, United States
Saint Luke's Hospital of Duluth

Duluth, Minnesota, 55805, United States
Saint Vincent Hospital Cancer Center Green Bay

Green Bay, Wisconsin, 54301, United States
Saint Vincent Hospital Cancer Center at Saint Mary's

Green Bay, Wisconsin, 54303, United States
Sanford Bismarck Medical Center

Bismarck, North Dakota, 58501, United States
Self Regional Healthcare

Greenwood, South Carolina, 29646, United States
Southwest Illinois Health Services LLP

Swansea, Illinois, 62226, United States
Spartanburg Medical Center

Spartanburg, South Carolina, 29303, United States
Sutter Medical Center Sacramento

Sacramento, California, 95816, United States
Texas Oncology-Austin Midtown

Austin, Texas, 78705, United States
The Cancer Center of Hawaii-Liliha

Honolulu, Hawaii, 96817, United States
The Permanente Medical Group-Roseville Radiation Oncology

Roseville, California, 95678, United States
The Research Institute of the McGill University Health Centre (MUHC)

Montreal, Quebec, H3H 2R9, Canada
Tom Baker Cancer Centre

Calgary, Alberta, T2N 4N2, Canada
UC Irvine Health/Chao Family Comprehensive Cancer Center

Orange, California, 92868, United States
UC San Diego Moores Cancer Center

La Jolla, California, 92093, United States
UCHealth Memorial Hospital Central

Colorado Springs, Colorado, 80909, United States
UCHealth University of Colorado Hospital

Aurora, Colorado, 80045, United States
UM Upper Chesapeake Medical Center

Bel Air, Maryland, 21014, United States
UNC Lineberger Comprehensive Cancer Center

Chapel Hill, North Carolina, 27599, United States
UNC Rex Cancer Center of Wakefield

Raleigh, North Carolina, 27614, United States
UNC Rex Healthcare

Raleigh, North Carolina, 27607, United States
UPMC Pinnacle Cancer Center/Community Osteopathic Campus

Harrisburg, Pennsylvania, 17109, United States
UPMC-Shadyside Hospital

Pittsburgh, Pennsylvania, 15232, United States
USC / Norris Comprehensive Cancer Center

Los Angeles, California, 90033, United States
UT Southwestern/Simmons Cancer Center-Dallas

Dallas, Texas, 75390, United States
University of Alabama at Birmingham Cancer Center

Birmingham, Alabama, 35233, United States
University of California Davis Comprehensive Cancer Center

Sacramento, California, 95817, United States
University of Chicago Comprehensive Cancer Center

Chicago, Illinois, 60637, United States
University of Florida Health Science Center - Gainesville

Gainesville, Florida, 32610, United States
University of Illinois

Chicago, Illinois, 60612, United States
University of Maryland/Greenebaum Cancer Center

Baltimore, Maryland, 21201, United States
University of Michigan Comprehensive Cancer Center

Ann Arbor, Michigan, 48109, United States
University of Nebraska Medical Center

Omaha, Nebraska, 68198, United States
University of New Mexico Cancer Center

Albuquerque, New Mexico, 87102, United States
University of Oklahoma Health Sciences Center

Oklahoma City, Oklahoma, 73104, United States
University of Pennsylvania/Abramson Cancer Center

Philadelphia, Pennsylvania, 19104, United States
University of Rochester

Rochester, New York, 14642, United States
Virtua Memorial

Mount Holly, New Jersey, 08060, United States
Virtua Voorhees

Voorhees Township, New Jersey, 08043, United States
Wake Forest University Health Sciences

Winston-Salem, North Carolina, 27157, United States
Washington University School of Medicine

St Louis, Missouri, 63110, United States
Wentworth-Douglass Hospital

Dover, New Hampshire, 03820, United States
West Michigan Cancer Center

Kalamazoo, Michigan, 49007, United States
West Virginia University Healthcare

Morgantown, West Virginia, 26506, United States
William Beaumont Hospital-Royal Oak

Royal Oak, Michigan, 48073, United States
Yonsei University Health System-Severance Hospital

Seoul, 120-752, South Korea

Conditions

Explore the condition pages connected to this study.

ANATOMIC STAGE IV BREAST CANCER AJCC V8 ANATOMIC STAGE IV BREAST CANCER AMERICAN JOINT COMMITTEE ON CANCER (AJCC) V8 METASTATIC BREAST CARCINOMA METASTATIC MALIGNANT NEOPLASM IN THE BONE METASTATIC MALIGNANT NEOPLASM IN THE LIVER METASTATIC MALIGNANT NEOPLASM IN THE LUNG METASTATIC MALIGNANT NEOPLASM IN THE LYMPH NODES METASTATIC MALIGNANT NEOPLASM IN THE SPINE PROGNOSTIC STAGE IV BREAST CANCER AJCC V8