Could a gentler start to cancer treatment reduce harsh side effects?
NCT ID NCT06001762
Summary
This study is testing if starting with a lower dose of the cancer drug abemaciclib and slowly increasing it is easier for patients to tolerate than the standard full dose. It involves 90 people with early-stage, high-risk, hormone-positive breast cancer who have already had surgery. The main goal is to see if this approach causes fewer side effects, like severe diarrhea, which often leads patients to stop or reduce their medication.
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Contacts and locations
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Locations
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Beth Israel Deaconess Medical Center
Boston, Massachusetts, 02215, United States
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Boston Medical Center
Boston, Massachusetts, 02118, United States
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Dana-Farber Cancer Insitute at Londonderry Hospital
Londonderry, New Hampshire, 03053, United States
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Dana-Farber Cancer Institute
Boston, Massachusetts, 02215, United States
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Dana-Farber Cancer Institute at Foxborough
Foxborough, Massachusetts, 02035, United States
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Dana-Farber Cancer Institute at Merrimack Valley
Methuen, Massachusetts, 01844, United States
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Dana-Farber Cancer Institute at Milford
Milford, Massachusetts, 01757, United States
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Dana-Farber Cancer Institute at South Shore
South Weymouth, Massachusetts, 02190, United States
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Dana-Farber Cancer Institute at Steward St. Elizabeth's
Brighton, Massachusetts, 02135, United States
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Eastern Maine Medical Center (Northern Light)
Brewer, Maine, 04412, United States
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New England Cancer Specialists
Scarborough, Maine, 04074, United States
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Stamford Hospital
Stamford, Connecticut, 06904, United States
Conditions
Explore the condition pages connected to this study.