New hope for advanced breast cancer: testing powerful drug combos

NCT ID NCT05563220

Recruiting now Disease control Sponsor: Stemline Therapeutics, Inc. Source: ClinicalTrials.gov ↗

Summary

This study is testing a new drug, elacestrant, combined with other cancer medicines to see if they can better control advanced breast cancer that has spread. It will involve about 435 adults whose cancer has worsened despite prior hormone therapy. The first part finds safe doses, and the second part checks how well the combinations work to slow the cancer's growth.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

ACCG - Hospital Araujo Jorge
RECRUITING

Goiânia, 74605-070, Brazil

Contact
ASST degli Spedali Civili di Brescia
RECRUITING

Brescia, 25123, Italy

Contact
Abdurrahman Yurtaslan Oncology Hospital
RECRUITING

Ankara, 0*6200, Turkey (Türkiye)

Contact
Advent Health (Florida Hospital) - Altamonte Springs
RECRUITING

Altamonte Springs, Florida, 32701, United States

Contact
Algemeen Ziekenhuis Nikolaas; VITAZ; Oncologie Klinisch Studiecentrum
WITHDRAWN

Sint-Niklaas, 09100, Belgium
Ankara Bilkent City Hospital, Bilkent Campus, Universiteler Mh. (old: Ankara Yildirim Beyazit Universitesi)
WITHDRAWN

Ankara, 6001CD, Turkey (Türkiye)
Asan Medical Center
RECRUITING

Seoul, 05505, South Korea

Contact
Astera Cancer Care
RECRUITING

East Brunswick, New Jersey, 08816, United States

Contact
Azienda Ospedaliera "Istituti Ospitalieri" Di Cremona
WITHDRAWN

Cremona, 26100, Italy
Azienda Ospedaliero-Universitaria Pisana
WITHDRAWN

Pisa, 56124, Italy
Barbara Ann Karmanos Cancer Institute
RECRUITING

Detroit, Michigan, 48201, United States

Contact
Cancer Care Northwest
RECRUITING

Spokane Valley, Washington, 99216, United States

Contact
Cedars Sinai
RECRUITING

Los Angeles, California, 90048, United States

Contact
Cemaic - Centro De Especialidades Medicas Ambulatorias E Investigacion Clinica
RECRUITING

Córdoba, X5008HHW, Argentina

Contact
Centre Hospitalier De L'Ardenne
RECRUITING

Libramont, 06800, Luxembourg

Contact
Centre Hospitalier Lyon SUD- HCL
RECRUITING

Lyon, 69495, France

Contact
Centre Hospitalier Universitaire (Chu) De Toulouse - Institut Universitaire Du Cancer De Toulouse-Oncopole (Iuct-Oncopole) (Institut Claudius Regaud)
RECRUITING

Toulouse, 31059 Cedex 09, France

Contact
Centre de Cancérologie du Grand Montpellier
RECRUITING

Montpellier, 34070, France

Contact
Centre de Cancérologie du Grand Montpellier
RECRUITING

Rouen, 76038 Cedex 1, France

Contact
Centro Gaucho Integrado de Oncologia; Hematologia; Ensino e Pesquisa - Hospital Mae de Deus/AESC
RECRUITING

Porto Alegre, 90850-170, Brazil

Contact
Centro Medico Austral
RECRUITING

Buenos Aires, C1017AAS, Argentina

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Centro Oncologico Riojano Integral (Cori)
RECRUITING

La Rioja, 01122, Argentina

Contact
City of Hope National Medical Center
NOT_YET_RECRUITING

Duarte, California, 91010, United States

Contact
Clinica Neoplasias Litoral
RECRUITING

Itajaí, 88301-220, Brazil

Contact
Complejo Hospitalario Universitario A Coruna
RECRUITING

A Coruña, 15006, Spain

Contact
Cooperman Barnabas Medical Center
RECRUITING

New Brunswick, New Jersey, 08901, United States

Contact
Dana Farber Cancer Institute
RECRUITING

Boston, Massachusetts, 02215, United States

Contact
Davidoff Rabin Medical Center
RECRUITING

Petah Tikva, 49100, Israel

Contact
Dothan Hematology and Oncology
RECRUITING

Dothan, Alabama, 36303, United States

Contact
Fakultni Nemocnice Olomouc
WITHDRAWN

Olomouc, 77900, Czechia
Fort Wayne Medical Oncology and Hematology
WITHDRAWN

Fort Wayne, Indiana, 46804, United States
Fundacion Instituto Valeciano De Oncologia
RECRUITING

Valencia, 46009, Spain

Contact
Gangnam Severance Hospital
RECRUITING

Seoul, 06273, South Korea

Contact
George Washington Cancer Center
RECRUITING

Washington D.C., District of Columbia, 20037, United States

Contact
Gesundheit Nordhessen Klinikum Kassel
WITHDRAWN

Kassel, 34125, Germany
Glendale Adventist
WITHDRAWN

Glendale, California, 91206, United States
Grand Hôpital de Charleroi - Site Notre Dame
RECRUITING

Charleroi, 06000, Belgium

Contact
Highlands Oncology Group
RECRUITING

Springdale, Arkansas, 72762, United States

Contact
Hospital Arnau De Vilanova
RECRUITING

Valencia, 46015, Spain

Contact
Hospital Britanico De Buenos Aires
WITHDRAWN

Buenos Aires, C1280 AEB, Argentina
Hospital Clinic Barcelona
RECRUITING

Barcelona, 08036, Spain

Contact
Hospital Clinico San Carlos
RECRUITING

Madrid, 28040, Spain

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Hospital Clinico Universitario de Valencia
RECRUITING

Valencia, 46010, Spain

Contact
Hospital General Universitario Gregorio Maranon
RECRUITING

Madrid, 28007, Spain

Contact
Hospital Sao Lucas da PUCRS
RECRUITING

Porto Alegre, 90610-000, Brazil

Contact
Hospital Sirio-Libanes (HSL) - Centro De Oncologia - Sao Paulo
RECRUITING

São Paulo, 01308-050, Brazil

Contact
Hospital Universitari Vall d'Hebron
RECRUITING

Barcelona, 08035, Spain

Contact
Hospital Universitario 12 de Octubre
RECRUITING

Madrid, 28041, Spain

Contact
Hospital Universitario La Paz
RECRUITING

Madrid, 28046, Spain

Contact
Hospital Universitario Virgen de la Victoria
RECRUITING

Málaga, 29010, Spain

Contact
IOB Madrd Institute of Oncology Hospital Beata Maria Ana de Jesus
RECRUITING

Madrid, 28007, Spain

Contact
Inova Schar Cancer Institute
WITHDRAWN

Fairfax, Virginia, 22031, United States
Institut Gustave-Roussy-Umr 981
RECRUITING

Villejuif, 94805, France

Contact
Institut Jules Bordet
RECRUITING

Anderlecht, 01070, Belgium

Contact
Instytut Centrum Zdrowia Matki Polki
WITHDRAWN

Lodz, 93-338, Poland
Istituto Europeo di Oncologia (IEO)
RECRUITING

Milan, 20141, Italy

Contact
Istituto Nazionale Tumori "Fondazione PASCALE"
RECRUITING

Naples, 80131, Italy

Contact
Johns Hopkins School of Medicine
RECRUITING

Baltimore, Maryland, 21287, United States

Contact
Klinika Onkologii; Wojskowy Instytut Medyczny - Państwowy Instytut Badawczy
WITHDRAWN

Warsaw, Masovian Voivodeship, 04-141, Poland
Kliniken Essen-Mitte (KEM)
WITHDRAWN

Essen, 45136, Germany
Korea University Anam Hospital
WITHDRAWN

Seoul, 136-705, South Korea
Liverpool Hospital
WITHDRAWN

Liverpool, NSW 2170, United Kingdom
MD Alliance for Multispecialty Research, LLC
RECRUITING

Merriam, Kansas, 66204, United States

Contact
MD Anderson Cancer Center Texas
RECRUITING

Houston, Texas, 77030, United States

Contact
Macquarie University
RECRUITING

Sydney, 2113, Australia

Contact
Marienhospital Bottrop
WITHDRAWN

Bottrop, 46236, Germany
Massachusetts General Hospital
RECRUITING

Boston, Massachusetts, 02114, United States

Contact
Mayo Clinic - Arizona
RECRUITING

Phoenix, Arizona, 85054, United States

Contact
Mayo Clinic - Jacksonville
RECRUITING

Jacksonville, Florida, 32224, United States

Contact
Mayo Clinic - Rochester
RECRUITING

Rochester, Minnesota, 55905, United States

Contact
Med-Polonia Sp. Z o.o.
WITHDRAWN

Poznan, 60-693, Poland
Minnesota Oncology Hematology
WITHDRAWN

Minneapolis, Minnesota, 55404, United States
NEXT Madrid
RECRUITING

Pozuelo de Alarcón, 28223, Spain

Contact
NYU Langone Health
RECRUITING

New York, New York, 10016, United States

Contact
Nemocnice Horovice Hospital
WITHDRAWN

Hořovice, 26831, Czechia
New England Cancer Specialists
WITHDRAWN

Scarborough, Maine, 04074, United States
New York Cancer and Blood Specialists
WITHDRAWN

Port Jefferson Station, New York, 11776, United States
North Middlesex University Hospital
RECRUITING

London, N18 1QX, United Kingdom

Contact
Northside Hospital Atlanta Cancer Care
WITHDRAWN

Cumming, Georgia, 30041, United States
Northwest Medical Specialties (Nwms) - Puyallup - Medical Oncology (Rainier Hematology-Oncology)/Exigent Research Network; LLC
RECRUITING

Tacoma, Washington, 98405, United States

Contact
Northwestern Feinberg Scholl of Medicine Prentice Women's Hospital
RECRUITING

Chicago, Illinois, 60611, United States

Contact
OPN Healthcare (Arcadia Location)
WITHDRAWN

Arcadia, California, 91007, United States
OPN Healthcare (Los Alamitos Location)
RECRUITING

Los Alamitos, California, 90720, United States

Contact
Ocala Oncology
WITHDRAWN

Ocala, Florida, 34474, United States
Orszagos Onkologiai Intezet
WITHDRAWN

Budapest, 01122, Hungary
Ospedale Infermi di Rimini - Azienda Unita Sanitaria Locale Della Romagna
RECRUITING

Rimini, 47923, Italy

Contact
Przychodnia Lekarska "Komed" Roman Karaszewski
WITHDRAWN

Konin, 62-500, Poland
Rambam Heath
RECRUITING

Haifa, 352408, Israel

Contact
Rocky Mountain Cancer Centers
RECRUITING

Lone Tree, Colorado, 80124, United States

Contact
Samson Assuta Ashdod University Hospital - The Institute of Oncology
RECRUITING

Ashdod, 7747629, Israel

Contact
Sarah Cannon Research Institute / Tennessee Oncology
RECRUITING

Nashville, Tennessee, 37203, United States

Contact
Sarah Cannon Research Institute UK; Ltd
RECRUITING

London, W1G 6AD, United Kingdom

Contact
Semmelweis Egyetem Klinikai Kozpont - Onkologiai Intezet
WITHDRAWN

Budapest, 01083, Hungary
Seoul National University Bundang Hospital
RECRUITING

Seongnam-si, 13620, South Korea

Contact
Shaare Zedek Medical Center
RECRUITING

Jerusalem, 9103102, Israel

Contact
Sheba Medical Center; Center Israel
RECRUITING

Ramat Gan, 5265601, Israel

Contact
Summit Medical Group
RECRUITING

Florham Park, New Jersey, 07932, United States

Contact
TOI Clinical Research
COMPLETED

Whittier, California, 90603, United States
Technischen Universitaet Muenchen (TUM), Klinikum Rechts der Isar
WITHDRAWN

Munich, Bavaria, 81675, Germany
Texas Oncology - Baylor Charles A. Sammons Cancer Center
RECRUITING

Dallas, Texas, 75246, United States

Contact
The Catholic University of Korea - Seoul St. Mary's Hospital
WITHDRAWN

Seoul, 06591, South Korea
The Clatterbridge Cancer Centre NHS Foundation Trust
RECRUITING

Liverpool, L7 8YA, United Kingdom

Contact
UCLA UCLA Hem/Onc - Clinical Research Unit
RECRUITING

Los Angeles, California, 90095, United States

Contact
UCSF Helen Diller Family Comprehensive Cancer Center
RECRUITING

San Francisco, California, 94158, United States

Contact
UT Health San Antonio
RECRUITING

San Antonio, Texas, 78229, United States

Contact
Ulsan University Hospital
WITHDRAWN

Ulsan, 44033, South Korea
Universitaetsklinikum Mannheim
WITHDRAWN

Mannheim, Baden-Wurttemberg, 68167, Germany
Universitaetsklinikum Tuebingen
WITHDRAWN

Tübingen, 72076, Germany
Universitaire Ziekenhuizen (Uz) Leuven - Campus Gasthuisberg - Multidisciplinair Borstcentrum (Multidisciplinary Breast Center) (Mbc)
RECRUITING

Leuven, 03000, Belgium

Contact
Universitatskinikum Carl Gustav Carus Dresden
WITHDRAWN

Dresden, Saxony, 01307, Germany
Universitatskinikum Carl Gustav Carus Dresden
WITHDRAWN

Dresden, 01307, Germany
University College London Hospitals NHS Foundation Trust; The London Clinic - Main Hospital
RECRUITING

London, W1T 7HA, United Kingdom

Contact
University of WI - Carbone Cancer Center (Phase II only)
RECRUITING

Madison, Wisconsin, 53792, United States

Contact
Virginia Cancer Specialists
RECRUITING

Fairfax, Virginia, 22031, United States

Contact
Virginia Oncology Associates
RECRUITING

Norfolk, Virginia, 23502, United States

Contact
W&IH of RI Breast Health Center of Women and Infants Hospital of Rhode Island
RECRUITING

Providence, Rhode Island, 02905, United States

Contact
Washington University School of Medicine in St. Louis
RECRUITING

St Louis, Missouri, 63110, United States

Contact
Yale School Of Medicine - Smilow Cancer Hospital - Breast Center
WITHDRAWN

New Haven, Connecticut, 06519, United States

Conditions

Explore the condition pages connected to this study.

BREAST CANCER METASTATIC BREAST CANCER