Russian study maps BRCA mutations in early breast cancer
NCT ID NCT05939128
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at 625 people in Russia with high-risk early-stage breast cancer that is HER2-negative. Researchers want to find out how many have BRCA1 or BRCA2 gene mutations and what treatments they receive in real-world practice. Participants provide blood and tumor samples for genetic testing, and their health is followed over time. This is an observational study, meaning no new treatment is being tested.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this study could help doctors better understand how common BRCA1/2 mutations are in this group and how treatment is currently managed, potentially guiding future care decisions.
What could go wrong
This is an observational study, not a treatment trial, so it won't directly improve outcomes for participants. Results may not apply to patients outside Russia.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for BREAST CANCER are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Research Site
Arkhangelsk, Russia
-
Research Site
Barnaul, Russia
-
Research Site
Belgorod, Russia
-
Research Site
Chelyabinsk, Russia
-
Research Site
Grozny, Russia
-
Research Site
Irkutsk, Russia
-
Research Site
Khanty-Mansiysk, Russia
-
Research Site
Krasnodar, Russia
-
Research Site
Krasnoyarsk, Russia
-
Research Site
Moscow, Russia
-
Research Site
Nal'chik, Russia
-
Research Site
Nyzhny Novgorod, Russia
-
Research Site
Ryazan, Russia
-
Research Site
Saint Petersburg, Russia
-
Research Site
Severodvinsk, Russia
-
Research Site
Sochi, Russia
-
Research Site
Ufa, Russia
-
Research Site
Vladivostok, Russia
-
Research Site
Yaroslavl, Russia