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10,000 women with BRCA mutations join national study to unlock cancer prevention secrets

NCT ID NCT07253051

Recruiting now Knowledge-focused Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is collecting health information from 10,000 women in Italy who carry BRCA1 or BRCA2 gene mutations, which raise the risk of certain cancers. Researchers aim to better understand where these mutations are most common and how to improve care. Participants simply provide their medical data through a secure platform; no experimental treatments are given.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could help identify high-risk areas and improve prevention strategies for BRCA-related cancers.
What could go wrong
This is an observational study, not a treatment trial. It collects data only and does not test any intervention, so direct health benefits are not guaranteed.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

BRCA1-related cancer predisposition BRCA2-related cancer predisposition

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BRCA1 MUTATION BRCA2 MUTATION

Contacts and locations

Locations

  • ASST Papa Giovanni XXIII

    NOT_YET_RECRUITING

    Bergamo, 24127, Italy

  • AULSS 8 Berica

    NOT_YET_RECRUITING

    Vicenza, 36100, Italy

  • Azienda Ospedaliera Universitaria Integrata

    NOT_YET_RECRUITING

    Verona, 37126, Italy

  • Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone

    NOT_YET_RECRUITING

    Palermo, 90127, Italy

  • Azienda Ospedaliera Universitaria Senese

    NOT_YET_RECRUITING

    Siena, 53100, Italy

  • Azienda Ospedaliera Universitaria di Parma

    NOT_YET_RECRUITING

    Parma, 43126, Italy

  • Azienda Ospedaliero Santa Croce e Carle

    NOT_YET_RECRUITING

    Cuneo, 12100, Italy

  • Azienda Ospedaliero Universitaria Careggi, Oncologia Medica Ginecologica

    NOT_YET_RECRUITING

    Florence, 50134, Italy

  • Azienda Ospedaliero Universitaria Citta della Salute e della Scienza di Torino

    NOT_YET_RECRUITING

    Torino, 10126, Italy

  • Azienda Ospedaliero Universitaria Pisana

    NOT_YET_RECRUITING

    Pisa, 56100, Italy

  • Azienda Ospedaliero-Universitaria di Parma

    NOT_YET_RECRUITING

    Parma, 43126, Italy

  • Azienda ULSS 2 MARCA TREVIGIANA

    NOT_YET_RECRUITING

    Treviso, 31100, Italy

  • Azienda sanitaria universitaria Friuli Centrale

    NOT_YET_RECRUITING

    Tolmezzo, 33028, Italy

  • Centro Nazionale di Adroterapia Oncologica

    NOT_YET_RECRUITING

    Pavia, 27100, Italy

  • Centro di Riferimento Oncologico IRCCS

    NOT_YET_RECRUITING

    Aviano, 33081, Italy

  • Fondazione I.R.C.C.S. Policlinico San Matteo

    NOT_YET_RECRUITING

    Pavia, 27100, Italy

  • Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico

    NOT_YET_RECRUITING

    Milan, 20133, Italy

  • Fondazione IRCCS San Gerardo dei Tintori

    RECRUITING

    Monza, 20900, Italy

  • Fondazione Policlinico Universitario Agostino Gemelli IRCCS, UOC Ginecologia Oncologica

    RECRUITING

    Rome, 00168, Italy

  • Humanitas San Pio X - Milano

    NOT_YET_RECRUITING

    Milan, 20159, Italy

  • IRCCS Istituto Tumori "Giovanni Paolo II"

    RECRUITING

    Bari, 70124, Italy

  • IRCCS Ospedale Policlinico San Martino

    NOT_YET_RECRUITING

    Genova, 16132, Italy

  • IRCCS Ospedale San Raffaele

    NOT_YET_RECRUITING

    Milan, 20132, Italy

  • IRCCS materno infantile Burlo Garofolo

    NOT_YET_RECRUITING

    Trieste, 34137, Italy

  • Istituto Nazionale Tumori Fondazione G. Pascale

    RECRUITING

    Naples, 80131, Italy

  • Istituto Nazionale Tumori Regina Elena

    NOT_YET_RECRUITING

    Roma, 00144, Italy

  • Istituto Nazionale Tumori Regina Elena

    NOT_YET_RECRUITING

    Roma, 00144, Italy

  • Istituto Romagnolo per lo Studio dei Tumori "Dino Amadori"

    NOT_YET_RECRUITING

    Meldola, 47014, Italy

  • L'Azienda ospedaliera per l'emergenza "Cannizzaro"

    NOT_YET_RECRUITING

    Catania, 95126, Italy

  • Malzoni Research Hospital

    NOT_YET_RECRUITING

    Avellino, 83100, Italy

  • Ospedale G. Mazzini di Teramo

    NOT_YET_RECRUITING

    Teramo, 64100, Italy

  • Ospedale Mater Olbia

    NOT_YET_RECRUITING

    Olbia, 07026, Italy

  • Ospedale Mauriziano Umberto I

    NOT_YET_RECRUITING

    Torino, 10128, Italy

  • Ospedale S. Maria Goretti, Latina

    NOT_YET_RECRUITING

    Latina, 04100, Italy

  • Ospedale Vito Fazzi, Lecce

    NOT_YET_RECRUITING

    Lecce, 73100, Italy

  • Ospedale del Tigullio Polo di Lavagna - ASL 4 Chiavarese

    NOT_YET_RECRUITING

    Lavagna, 16033, Italy

  • Policlinico Umberto I Università "La Sapienza"

    NOT_YET_RECRUITING

    Roma, 00161, Italy

  • Presidio Ospedaliero Umberto I - ASP di Enna

    NOT_YET_RECRUITING

    Enna, 94100, Italy

  • Presidio Ospedaliero di Mirano

    NOT_YET_RECRUITING

    Mirano, 30035, Italy

  • Università degli Studi di Bari "Aldo Moro"

    NOT_YET_RECRUITING

    Bari, 70121, Italy

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