Can BRCA genes predict early menopause? new study seeks answers

NCT ID NCT00823654

Recruiting now Knowledge-focused Sponsor: Memorial Sloan Kettering Cancer Center Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how BRCA gene mutations and breast cancer treatments affect the ovaries in premenopausal women. Researchers will measure hormone levels in the blood before, during, and after cancer therapy to understand the risk of early menopause and fertility problems. About 609 women with early-stage breast cancer or high-risk BRCA mutations will participate. The goal is to learn which women are more likely to experience early menopause, helping guide future family planning decisions.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BREAST CANCER

Contacts and locations

Locations

Memorial Sloan Kettering Basking Ridge
RECRUITING

Basking Ridge, New Jersey, United States
Memorial Sloan Kettering Bergen
RECRUITING

Montvale, New Jersey, 07645, United States
Memorial Sloan Kettering Cancer Center
RECRUITING

New York, New York, 10065, United States
Memorial Sloan Kettering Commack
RECRUITING

Commack, New York, 11725, United States
Memorial Sloan Kettering Monmouth
RECRUITING

Middletown, New Jersey, 07748, United States
Memorial Sloan Kettering Nassau
RECRUITING

Uniondale, New York, 11553, United States
Memorial Sloan Kettering Westchester
RECRUITING

Harrison, New York, 10604, United States
New York Presbyterian Hospital-Weill Medical College of Cornell University
ACTIVE_NOT_RECRUITING

New York, New York, 10065, United States

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