Brain surgery gets a GPS: new trial aims to save speech and movement

NCT ID NCT07657403

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests whether using advanced brain network mapping (connectome-guided navigation) during surgery can better preserve functions like speech and movement in people with brain tumors in critical areas. Two hundred participants will be randomly assigned to either this new technique or standard surgery. The main goal is to see if more patients keep their neurological abilities six months after the operation.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Connectome-guided navigation-assisted microsurgical resection (a surgical procedure using brain network mapping to guide tumor removal)
What this could lead to
If successful, this could become a new standard for brain tumor surgery that better protects language, movement, and other critical functions.
What could go wrong
This is a single-center trial with 200 participants, so results may not apply to all patients. The technique is complex and may not always improve outcomes over standard methods.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College

    RECRUITING

    Beijing, 100021, China

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