Brain training targets voices in schizophrenia

NCT ID NCT05299749

Recruiting now Symptom relief Sponsor: Boston VA Research Institute, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests whether real-time fMRI neurofeedback can help people with schizophrenia who still hear voices despite medication. Participants learn to control their own brain activity while inside an MRI scanner, aiming to reduce the brain signals linked to auditory hallucinations. The trial will enroll 104 people and compare real feedback to a sham version.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: real-time fMRI neurofeedback
What this could lead to: If it works, this could offer a new, non-drug way to reduce distressing voices for people with schizophrenia who don't respond to medication.
What could go wrong: This is an early-stage study with a small number of participants. The effect may be small or not last long, and not everyone may benefit.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for AUDITORY HALLUCINATION are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Hallucinations schizoaffective disorder schizophrenia Schizophrenia, Treatment-Resistant treatment-refractory schizophrenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AUDITORY HALLUCINATION SCHIZOPHRENIA TREATMENT-RESISTANT SCHIZOPHRENIA

Contacts and locations

Locations

Boston VA Healthcare System, Brockton
RECRUITING

Brockton, Massachusetts, 02301, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.