Scientists use powerful MRI to uncover brain secrets behind flexible thinking

NCT ID NCT07217652

Recruiting now Knowledge-focused Sponsor: Kai Hwang Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study uses high-resolution 7-Tesla MRI to examine how a part of the brain called the mediodorsal thalamus supports flexible thinking and decision-making. One hundred healthy adults will perform computer tasks while their brain activity is scanned. The goal is to understand why people with conditions like schizophrenia and ADHD often struggle with cognitive flexibility.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this research could reveal how the brain's thalamus supports flexible thinking, potentially guiding future treatments for cognitive problems in schizophrenia and ADHD.
What could go wrong: This is an early-stage observational study, not a treatment trial. It may not lead directly to new therapies, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

attention deficit hyperactivity disorder, inattentive type attention deficit-hyperactivity disorder schizophrenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ATTENTION DEFICIT DISORDER WITH HYPERACTIVITY (ADHD) SCHIZOPHRENIA

Contacts and locations

Locations

The University of Iowa
RECRUITING

Iowa City, Iowa, 52242, United States

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