Brain zaps may unlock secrets of Decision-Making

NCT ID NCT06561828

Recruiting now Knowledge-focused Sponsor: National Institute on Drug Abuse (NIDA) Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Aug 14, 2026 · Updated 35 times

Summary

This study uses transcranial magnetic stimulation (TMS) to see how it affects brain activity during learning and decision-making tasks. Researchers will test up to 600 healthy adults aged 18-45. Participants may undergo TMS, brain scans, and computer tasks to measure responses.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Transcranial magnetic stimulation (TMS) using theta burst stimulation (continuous or intermittent) or a sham device
What this could lead to: If successful, this study could reveal how TMS changes brain activity related to learning and decision-making, potentially guiding future treatments for substance use disorder.
What could go wrong: This is a very early, small study in healthy volunteers, not patients. It focuses on basic brain function, not treatment. Results may not translate to clinical benefits.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for NORMAL PHYSIOLOGY are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NORMAL PHYSIOLOGY

Contacts and locations

Show contact details

Study contacts

Contact

Email: •••••@•••••

Locations

National Institute on Drug Abuse
RECRUITING

Baltimore, Maryland, 21224, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.