Brain pacemaker tested as last hope for severe depression

This study is testing whether deep brain stimulation (DBS), a surgical treatment sometimes called a 'brain pacemaker,' can help people with severe depression that hasn't improved with other treatments like multiple medications, therapy, or electroconvulsive therapy (ECT). Researchers will implant a small device to deliver electrical pulses to a specific brain area in up to 16 participants to see if it reduces their depression symptoms. The goal is to see if this approach is safe and effective for people who have run out of other options.