Double stimulation may boost leg recovery in spinal injury
NCT ID NCT07595497
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether adding brain stimulation to spinal cord stimulation can improve leg strength and walking in adults with chronic incomplete spinal cord injury. 24 participants will receive either combined therapy or spinal stimulation alone over 16 weeks. The goal is to see if the combined approach leads to better recovery of movement and function.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
About 24 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
-
Jan 2027
An estimate. Start dates often move.
- Expected to finish
-
Mar 2028
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 65 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria * Age 18-65 years at enrolment * Chronic traumatic spinal cord injury, defined as ≥12 months post-injury * Incomplete spinal cord injury, AIS grade C or D * Neurological level of injury from C2 to L1 * Baseline Lower Extremity Motor Score (LEMS) \>10 points * Medically stable * Able to provide informed consent * Able to commit to the full study duration * Able to attempt the 10-Meter Walk Test and 6-Minute Walk Test, with or - without assistive devices and standby assistance Exclusion Criteria * History of seizures or epilepsy * Implanted electronic devices, such as: Pacemaker, Cochlear implant, Deep brain stimulator, Spinal cord stimulator, Metallic implants in the head or spine * Pregnancy or planned pregnancy * Active psychiatric disorder or cognitive impairment * Concomitant neurological conditions, such as: Stroke, Traumatic brain injury and Neuropathy * Skin breakdown at electrode sites * Current participation in another clinical trial * History of skull surgery or craniotomy * Use of medications that alter cortical excitability within the past 2 weeks
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Spinal cord injuries (SCI) are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The places running it
1 site. The list below names each one and where it is.
-
The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
-
Alexandra Hospital/ National University Hospital, Singapore
Singapore, Singapore
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Mind over matter: can a brain implant restore hand control?
- Mind over matter: can a wireless brain implant restore control for the paralyzed?
- Can a home workout reawaken muscles after spinal cord injury?
- Can a robotic suit help kids with neurological conditions walk better?
- Can Mountain-Air breathing boost leg strength after spinal injury?
- Can science unlock the secret to a perfect wheelchair wheelie?