Can a home workout reawaken muscles after spinal cord injury?
NCT ID NCT07773974
First seen Aug 19, 2026 · Last updated Aug 20, 2026 · Updated 1 time
Summary
This study tests whether a 16-week home-based program combining functional electrical stimulation (FES) with high-intensity interval training (HIIT) is safe, practical, and acceptable for adults with spinal cord injury. Participants will use a portable FES device to activate paralyzed muscles during online group exercise sessions led by trainers. The goal is to see if this approach can improve muscle strength, fitness, and daily function, while also gathering feedback on what helps or hinders its use.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Functional electrical stimulation (FES) combined with high-intensity interval training (HIIT) delivered via a home-based virtual program
- What this could lead to
- If successful, this could offer a practical, home-based exercise option to improve muscle strength, fitness, and daily function for people with spinal cord injury.
- What could go wrong
- This is a small pilot study focused on feasibility, not proof of effectiveness. Results may not generalize, and there are risks of muscle spasms or discomfort from electrical stimulation.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 24 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Oct 2026
An estimate. Start dates often move.
- Expected to finish
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Jul 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Be an adult (i.e., ≥18 years old) with a SCI at T12 or above as individuals with a lower motor neuron condition are considered poor candidates for FES. 2. Have a SCI rated as American Spinal Injury Association Impairment Scale A, B, C or D. If no recent (i.e., in past six months) AIS rating is available in the medical record, the International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI) exam (Rupp et al. 2021) will be completed by the research team. 3. Be \>1 year post-injury, in the case of traumatic SCI, or \>1 year post-onset of neurological symptoms, in the case of a non-progressive, non-traumatic cause of SCI. 4. Be able to attend 8 assessment sessions and three education sessions at the Lyndhurst Centre or Rumsey Cardiac Rehab, as well as 36 FES+HIIT@Home sessions and one education session on Microsoft Teams. 5. Be ambulatory or use a manual wheelchair. 6. Be able to don/doff electrodes independently or with support from a family member or other caregiver. 7. Have physician clearance to participate in high intensity interval training (i.e., no contraindications to HIIT). 8. Have an emergency contact who can be reached by the research team during FES+HIIT@Home sessions. 9. Able to understand spoken English. Exclusion Criteria: 1. Presents with contraindications to FES (i.e. implanted electronic device, radiation in past six months, active deep vein thrombosis, pregnancy) (Houghton et al. 2010). 2. Presents with cognitive deficits that would prevent independent use of an FES device. 3. Has irritated and/or damaged skin in areas where the electrodes will be applied. 4. Has a cardiovascular morbidity that would limit exercise tolerance, as identified through pre-intervention cardiorespiratory fitness testing (e.g., complex arrhythmias). 5. Participant receives a Botox injection or begins a new therapy or exercise program during the first 20 weeks of the study (i.e., prior to the post-intervention assessments).
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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KITE Research Institute, Toronto Rehabilitation Institute-University Health Network
Toronto, Ontario, M4G 3V9, Canada
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Other studies related to the condition(s) this trial covers.
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