Brain stimulation study reveals empathy wiring in borderline personality disorder

NCT ID NCT06702215

Completed Knowledge-focused Sponsor: IRCCS Centro San Giovanni di Dio Fatebenefratelli Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at how the brain's 'mirror system' for touch works in people with borderline personality disorder (BPD). Researchers used a non-invasive brain stimulation technique called TMS to temporarily change brain activity while participants watched a hand being touched. The goal was to understand differences in empathy-related brain wiring. 71 people took part, including those with BPD and healthy volunteers.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: transcranial magnetic stimulation (TMS)
What this could lead to: If successful, this study could help explain how empathy works differently in people with borderline personality disorder.
What could go wrong: This is a small, early-stage study with no treatment goal. It only measures brain responses and may not lead to any direct benefit for patients.

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Conditions

The condition(s) this trial relates to.

borderline personality disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BORDERLINE PERSONALITY DISORDER (BPD)

Contacts and locations

Locations

IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli

Brescia, Brescia, 25125, Italy

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