When is the best time to zap brain tumors? new trial tests before, during, or after surgery
NCT ID NCT05871307
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This trial looks at the best time to give radiotherapy for brain metastases that can be surgically removed. It compares giving radiation before surgery, during surgery, or after surgery. The goal is to see which timing best prevents the tumor from coming back. About 90 adults with solid tumors that have spread to the brain will take part.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Radiotherapy (stereotactic radiosurgery or intraoperative radiation)
What this could lead to
If successful, this trial could identify the best timing for radiotherapy to improve local tumor control and reduce recurrence after brain metastasis surgery.
What could go wrong
This is a small, early-phase (phase II) exploratory trial with only 90 participants, so results may not be definitive or widely applicable. Different timings carry varying risks of radiation side effects or surgical complications.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Department of Radiotherapy, University of Heidelberg
Heidelberg, 69120, Germany