Nasal insulin spray reveals Brain's role in sugar control

NCT ID NCT06295640

Ongoing Knowledge-focused Sponsor: University of Ulm Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at how insulin in the brain influences the body's handling of sugar after a meal. About 31 healthy volunteers will drink a sugary solution and receive either insulin or a placebo via nasal spray. Researchers will measure how the body produces and uses sugar to understand the brain's role in metabolism and any differences between men and women.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: intranasal insulin spray
What this could lead to: If successful, this could reveal how the brain helps regulate blood sugar after eating, potentially guiding future treatments for metabolic disorders.
What could go wrong: This is a small, early-stage study in healthy people, so results may not apply to those with diabetes or other conditions. The intervention is short-term and not intended as a treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

glucose metabolism disease Insulin Resistance

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GLUCOSE METABOLISM DISORDERS

Contacts and locations

Locations

Universityhospital Ulm

Ulm, 89081, Germany

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