Brain insulin disruption: Antipsychotics' hidden metabolic toll in women

NCT ID NCT06251635

First seen Apr 02, 2026 · Last updated May 09, 2026 · Updated 2 times

Summary

This study looks at how antipsychotic drugs might disrupt insulin action in the brains of healthy young women, and how this changes across the menstrual cycle. Fifteen participants will receive olanzapine or a placebo, plus intranasal insulin, and undergo MRI scans. The goal is to understand why women on antipsychotics face higher rates of metabolic problems like diabetes.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Centre for Addiction and Mental Health (CAMH)

    RECRUITING

    Toronto, Ontario, M6J 1H3, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.