Brain insulin study targets antipsychotic side effects in women

NCT ID NCT06251635

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how antipsychotic drugs might cause metabolic problems in women by affecting how the brain responds to insulin. Researchers will give 15 healthy women a single dose of the antipsychotic olanzapine and insulin nasal spray, then use brain scans to see changes. The goal is to understand why women on these drugs have higher rates of diabetes and weight gain.

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Conditions

The condition(s) this trial relates to.

hyperinsulinism Insulin Resistance type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Centre for Addiction and Mental Health (CAMH)

    RECRUITING

    Toronto, Ontario, M6J 1H3, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••