New scan tracks brain inflammation after radiation in kids
NCT ID NCT05128903
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study uses a special PET scan to measure brain inflammation in children with medulloblastoma who receive whole-brain radiation. Twenty-two participants will be scanned four times over two years to see how inflammation changes. The goal is to understand how radiation affects the brain over time, which may help reduce long-term cognitive problems.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- [18F]DPA714 (a radioactive tracer for PET scans)
- What this could lead to
- If successful, this could help doctors predict and possibly prevent cognitive side effects from brain radiation in children.
- What could go wrong
- This is a small, early-phase study (22 participants) that only measures inflammation—it does not test a treatment. Results may not apply to all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
St.Jude Children's Research Hospital
Memphis, Tennessee, 38105, United States
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Other studies related to the condition(s) this trial covers.
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