Scientists map brain receptors in healthy volunteers using radioactive tracer

NCT ID NCT03520543

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This completed Phase 1 study involved 16 healthy men aged 20-35 to test a radioactive tracer called [11C]Yohimbine. Researchers used PET scans to see how the tracer binds to certain brain receptors and measured its effects after giving the drug clonidine. The goal was to understand the tracer's behavior in the brain, not to treat any disease.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
[11C]Yohimbine (a radioactive tracer) and clonidine (a drug)

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Service de Neurologie C - Hôpital Neurologique et Neurochirurgical Pierre Wertheimer, GHE

    Bron, 69500, France

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