New scan could spot Parkinson's protein in the brain
NCT ID NCT06303921
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-phase study tests a radioactive tracer called 11C-M503 to see if it can detect abnormal alpha-synuclein protein clumps in the brain, which are linked to Parkinson's disease and multiple system atrophy. About 70 adults aged 40-85 with Parkinson's, multiple system atrophy, progressive supranuclear palsy, or healthy volunteers will receive the tracer and undergo PET scans. The goal is to improve diagnosis by distinguishing these conditions based on brain imaging.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University of Pennsylvania
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
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Washington University in St. Louis
RECRUITINGSt Louis, Missouri, 63110, United States
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Yale New Haven Hospital
RECRUITINGNew Haven, Connecticut, 06510, United States
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Other studies related to the condition(s) this trial covers.
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