Brain clock may play role in diabetes risk
NCT ID NCT05314855
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This completed study looked at whether the brain's central clock (the suprachiasmatic nucleus) works differently in people with insulin resistance or type 2 diabetes. Researchers used advanced MRI scans to measure brain activity over 24 hours in 28 obese adults with varying insulin sensitivity. The goal was to understand how the brain clock might be involved in the development of insulin resistance.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could help explain how the brain's internal clock affects insulin resistance and type 2 diabetes, pointing toward new treatment targets.
What could go wrong
This is a small observational study (28 people) that only measures brain activity, not a treatment. It may not lead to any direct medical changes.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Amsterdam University Medical Centers, location AMC
Amsterdam, North Holland, 1105AZ, Netherlands