New drug combo tested for aggressive brain tumors

NCT ID NCT03514069

Summary

This early-stage study is testing whether adding an experimental drug called ruxolitinib to standard brain cancer treatment (radiation and chemotherapy) is safe for patients. Researchers want to find the highest dose of ruxolitinib that patients can tolerate without severe side effects. The study involves 60 adults with newly diagnosed, aggressive brain tumors called high-grade gliomas or glioblastoma.

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Contacts and locations

Locations

  • Cleveland Clinic Taussig Cancer institute, Case Comprehensive Cancer Center

    Cleveland, Ohio, 44195, United States

Conditions

Explore the condition pages connected to this study.