Experimental CAR t therapy takes on Hard-to-Treat prostate cancer

NCT ID NCT07543055

First seen Jun 25, 2026 · Last updated Jul 01, 2026 · Updated 4 times

Summary

This early-stage study tests BPX-601, a personalized CAR T cell therapy made from a patient's own immune cells, for advanced prostate cancer that has spread and stopped responding to other treatments. The trial will enroll 36 people to find the safest dose and check for side effects, while also seeing if the therapy can shrink tumors or lower PSA levels. It is not yet recruiting.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

BPX-601 (a CAR T cell therapy made from the patient's own immune cells)

What this could lead to

If successful, this could point toward a new treatment option for advanced prostate cancer that has stopped responding to standard therapies.

What could go wrong

This is an early Phase 1 trial with only 36 participants, so it is primarily testing safety and dosing. The treatment may not shrink tumors or could cause serious side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

castration-resistant prostate carcinoma metastatic prostate carcinoma Neoplasm Metastasis prostate cancer Recurrence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • John Theurer Cancer Center

    RECRUITING

    Hackensack, New Jersey, 07601, United States