Engineered immune cells take on Hard-to-Treat cancers
NCT ID NCT05120271
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-stage study tests a new treatment called BOXR1030 for people with advanced solid tumors that have a specific marker (GPC3). The treatment uses specially designed immune cells given after chemotherapy to help fight the cancer. The main goals are to check safety and find the best dose. About 7 adults aged 18 to 80 with certain cancers like liver or lung cancer are taking part.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Baylor Scott and White Research Institute
Dallas, Texas, 75246, United States
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Beatson Institute for Cancer Research Wolfson Wohl Cancer Research Centre
Glasgow, G61 1BD, United Kingdom
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Fred Hutchinson Cancer Center - Seattle Cancer Care Alliance (SCCA) Location
Seattle, Washington, 98109, United States
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Froedtert and Medical College of Wisconsin
Milwaukee, Wisconsin, 53226, United States
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Hoag Hospital Newport Beach
Newport Beach, California, 92663, United States
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The Royal Marsden NHS Foundation Trust
London, SW3 6JJ, United Kingdom
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University College London Hospitals NHS Foundation Trust
London, NW1 2PG, United Kingdom
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University of Texas MD Anderson Cancer Center
Houston, Texas, 77030-4008, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Could a simple scan and blood test outsmart liver cancer?
- Could a vaccine help fight Hard-to-Treat cancers?
- Could a tailored diet before surgery boost liver cancer recovery?
- Can a new PET tracer light up hidden cancers?
- A new test could reveal how radiation affects the liver
- Can an immunotherapy drug keep liver cancer at bay after surgery?