Engineered immune cells take on Hard-to-Treat cancers

NCT ID NCT05120271

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early-stage study tests a new treatment called BOXR1030 for people with advanced solid tumors that have a specific marker (GPC3). The treatment uses specially designed immune cells given after chemotherapy to help fight the cancer. The main goals are to check safety and find the best dose. About 7 adults aged 18 to 80 with certain cancers like liver or lung cancer are taking part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary โ€” we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cutaneous neuroendocrine carcinoma hepatocellular carcinoma myxoid liposarcoma myxoid/round cell liposarcoma squamous cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Baylor Scott and White Research Institute

    Dallas, Texas, 75246, United States

  • Beatson Institute for Cancer Research Wolfson Wohl Cancer Research Centre

    Glasgow, G61 1BD, United Kingdom

  • Fred Hutchinson Cancer Center - Seattle Cancer Care Alliance (SCCA) Location

    Seattle, Washington, 98109, United States

  • Froedtert and Medical College of Wisconsin

    Milwaukee, Wisconsin, 53226, United States

  • Hoag Hospital Newport Beach

    Newport Beach, California, 92663, United States

  • The Royal Marsden NHS Foundation Trust

    London, SW3 6JJ, United Kingdom

  • University College London Hospitals NHS Foundation Trust

    London, NW1 2PG, United Kingdom

  • University of Texas MD Anderson Cancer Center

    Houston, Texas, 77030-4008, United States