Botox shot during prostate surgery may calm bladder woes

NCT ID NCT07377929

Recruiting now Symptom relief Sponsor: Benaroya Research Institute Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether injecting Botox into the bladder during standard prostate surgery (TURP or Aquablation) can reduce bothersome symptoms like frequent or urgent urination after the operation. Twenty men with an enlarged prostate and overactive bladder will be enrolled. Researchers will track urinary retention, symptom scores, and hospital stays for 12 weeks after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: onabotulinumtoxinA (Botox)
What this could lead to: If it works, this could point toward a way to ease post-surgery bladder symptoms for men with BPH.
What could go wrong: This is a very small, early study with only 20 participants, so results may not apply widely. Adding Botox could also raise the risk of urinary retention or longer hospital stays.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for BENIGN PROSTATIC HYPERTROPHY (BPH) are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

benign prostatic hyperplasia Lower Urinary Tract Symptoms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BENIGN PROSTATIC HYPERTROPHY (BPH) LOWER URINARY TRACK SYMPTOMS

Contacts and locations

Locations

Virginia Mason Franciscan Health
RECRUITING

Seattle, Washington, 98101, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.