Botox shot into pelvis may ease painful sex, small trial hopes
NCT ID NCT07486830
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether Botox injections into the pelvic floor muscles can reduce pain in women with provoked vestibulodynia, a condition causing pain during intercourse. Fifty-four premenopausal women with overactive pelvic floor muscles will receive either Botox or a placebo. The main goal is to see if the treatment helps them tolerate a larger dilator with less pain.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
IncobotulinumtoxinA (Botox)
What this could lead to
If it works, this could offer a new treatment option for women with painful intercourse caused by overactive pelvic floor muscles.
What could go wrong
This is a small, early-phase trial with only 54 participants. The treatment may not work better than placebo, and injections carry risks like temporary muscle weakness or pain at the injection site.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
More trials for these conditions
Other studies related to the condition(s) this trial covers.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Center for VulvoVaginal Disorders
RECRUITINGWashington D.C., District of Columbia, 21012, United States
Contact Phone: •••-•••-••••
Contact Phone: •••-•••-••••
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Centers for Vulvovaginal Disorders, NY
RECRUITINGNew York, New York, 10036, United States
Contact Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••