Center For Vulvovaginal Disorders

This study tests whether Botox injections into the pelvic floor muscles can reduce pain in women with provoked vestibulodynia, a condition causing pain during intercourse. Fifty-four premenopausal women with overactive pelvic floor muscles will receive either Botox or a placebo. …

This study tests a cream called ketotifen fumarate for women who experience sharp or burning pain during vaginal penetration, a condition known as secondary vestibulodynia. About 54 women will apply the cream or a placebo to the painful area twice daily for 12 weeks. Researchers …