New pacemaker technique aims to prevent heart damage
NCT ID NCT05869500
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study compares a newer pacing method called left bundle branch area pacing (LBBAP) with standard right ventricular pacing in 100 adults who need a pacemaker but have normal heart function. The goal is to see if LBBAP better prevents the decline in heart pumping ability that can occur with standard pacing. Participants will be randomly assigned to receive one of the two pacemaker types and followed for changes in heart function.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Left bundle branch area pacemaker (device) vs. right ventricular pacemaker (device)
What this could lead to
If successful, this could show that left bundle area pacing is a better standard option for preventing heart damage in people who need a pacemaker.
What could go wrong
This is a relatively small, early-stage study (100 participants) comparing two device approaches. The procedure for left bundle area pacing is newer and may have higher technical difficulty or unknown long-term risks.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Brigham and Women's Hospital
Boston, Massachusetts, 02115, United States
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Massachusetts General Hospital
Boston, Massachusetts, 02114, United States