New drug combo may make Half-Matched bone marrow transplants safer

NCT ID NCT02996773

First seen Nov 11, 2025 · Last updated Jun 16, 2026 · Updated 32 times

Summary

This study looked at a new way to do bone marrow transplants for people with blood cancers like leukemia and lymphoma who don't have a perfectly matched donor. Instead of using the standard drug cyclophosphamide after transplant, doctors tested replacing it with another drug called bendamustine to see if it was safe and worked well. About 50 patients took part, and the goal was to reduce side effects like graft-versus-host disease while still helping the new marrow grow.

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Contacts and locations

Locations

  • The University of Arizona Cancer Center

    Tucson, Arizona, 85724, United States

Conditions

Explore the condition pages connected to this study.