New bone graft cocktail shows promise for stubborn fractures
NCT ID NCT07561788
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a mixture of the patient's own bone, artificial bone substitute, antibiotic, and fresh blood to help heal leg fractures that had not joined properly. Twenty-five adults with broken thigh or shin bones that failed to heal after initial surgery received this composite graft. Researchers tracked bone healing on X-rays and pain levels for at least a year to see if the approach worked.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
composite graft (cancellous bone autograft, bone substitute, local antibiotic, and fresh blood)
What this could lead to
If successful, this approach could offer a reliable surgical option to heal stubborn broken bones that haven't joined properly.
What could go wrong
This was a small, single-center study with only 25 patients and no comparison group, so results may not apply to everyone. Infection or incomplete healing remain possible.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Tanta University
Tanta, El-Gharbia, 31527, Egypt