Why do some bones age faster? researchers dig into DXA scans for clues
NCT ID NCT07836868
First seen Sep 23, 2026 · Last updated Sep 23, 2026
Summary
Researchers at Mardin Artuklu University are reviewing existing medical records and DXA bone density scans from about 750 adults aged 40 and older. They want to understand how metabolic and clinical factors relate to bone mineral density measured at the lower spine and hip. The study also compares T-score differences between those two sites and looks at fracture history and FRAX risk scores. No new tests or treatments are given; the work relies entirely on data already collected.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If the patterns hold, this could sharpen how doctors read DXA scans and spot people at higher risk of fractures before bones break.
- What could go wrong
- This is a retrospective review of existing records, so it can show links but not cause and effect. Findings from one region's patients may not apply everywhere, and missing lab data could limit what researchers can conclude.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 750 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jul 2026
- Expected to finish
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Nov 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Adults aged 40 years and older who underwent lumbar spine and femoral neck DXA examination at Mardin Training and Research Hospital will be identified from existing hospital records. Patients with eligible DXA measurements and available clinical and laboratory data will be included. The study population may include individuals with normal bone mineral density, osteopenia, or osteoporosis. No healthy control group will be recruited separately.
- Ages
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40 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults aged 40 years or older * Lumbar spine (L1-L4) and femoral neck DXA measurements performed during the same assessment * Available T-score and bone mineral density data from the DXA examination * Available clinical and laboratory data required for the study analyses Exclusion Criteria: * Metal implant or prosthesis affecting lumbar spine or femoral neck DXA measurements * Unreliable lumbar spine measurement due to marked artifact, surgical material, vertebral compression fracture, or extensive degenerative changes * Fewer than two lumbar vertebrae suitable for analysis * Active malignancy * Stage 4 or higher chronic kidney disease * Metabolic bone disease that may substantially affect bone mineral density * Long-term systemic glucocorticoid use * Missing or uninterpretable DXA data
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Mardin Training and Research Hospital
Mardin, 47100, Turkey (Türkiye)
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