New drug BMS-986435 tested in liver health study
NCT ID NCT07248839
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-stage study is testing how the drug BMS-986435 behaves in the body and whether it is safe for people with mild to moderate liver problems compared to those with healthy livers. 24 adults will receive a single dose, and researchers will measure drug levels and monitor for side effects. The goal is to understand how liver function affects the drug, not to treat any disease directly.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
BMS-986435 (also known as MYK-224)
What this could lead to
If successful, this study could help determine safe dosing of BMS-986435 for people with liver problems, potentially leading to better treatment options for heart conditions.
What could go wrong
This is a very early (Phase 1) study with only 24 participants, so results may not apply to larger populations. The drug may cause side effects or not work as expected in people with liver impairment.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Locations
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Arizona Clinical Trials
RECRUITINGChandler, Arizona, 85225, United States
Contact Phone: •••-•••-••••
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Panax Clinical Research
RECRUITINGMiami Lakes, Florida, 33014, United States
Contact Phone: •••-•••-••••
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Texas Liver Institute
RECRUITINGSan Antonio, Texas, 78215, United States
Contact Phone: •••-•••-••••