Blue light may boost brain stimulation for Tough-to-Treat epilepsy
NCT ID NCT06304389
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study explores whether blue light can enhance the effects of vagus nerve stimulation (VNS) in people with refractory epilepsy. Researchers will measure brain activity, heart signals, and pupil size in 34 participants (including healthy volunteers) during light exposure and nerve stimulation. The goal is to understand how blue light might improve VNS, potentially leading to better seizure control.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- blue light
- What this could lead to
- If it works, this could point toward a way to make vagus nerve stimulation more effective for people with epilepsy.
- What could go wrong
- This is a small, early-stage study (34 people) that only measures short-term brain and pupil responses, not seizure reduction. It may not lead to a practical treatment.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Cliniques Universitaires Saint Luc
RECRUITINGWoluwe-Saint-Lambert, 1200, Belgium
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