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Stroke recovery: which blood pressure target works best?

NCT ID NCT06352619

Recruiting now Disease control Sponsor: The George Institute Source: ClinicalTrials.gov ↗

First seen Jul 08, 2026 · Last updated Jul 09, 2026 · Updated 1 time

Summary

This trial tests three different blood pressure management strategies in people who have had a stroke and received endovascular therapy (a procedure to remove a clot). The goal is to find the safest and most effective way to lower blood pressure after treatment to improve recovery. Up to 2,000 participants with high blood pressure after their procedure will be randomly assigned to conservative, moderate, or intensive blood pressure lowering. The study measures functional outcomes using the modified Rankin Scale, which assesses disability and independence.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Blood pressure management (conservative, moderate, or intensive lowering)
What this could lead to
If successful, this trial could identify the best blood pressure target after stroke treatment, potentially improving recovery and reducing disability.
What could go wrong
This is an early-stage trial comparing strategies, not a proven treatment. Previous studies have shown conflicting results, and intensive blood pressure lowering may cause harm.

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Conditions

The condition(s) this trial relates to.

ischemic stroke

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ISCHEMIC STROKE, ACUTE

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The George Institute for Global Health

    RECRUITING

    Sydney, New South Wales, 2000, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Calgary

    RECRUITING

    Calgary, Alberta, T2N 1N4, Canada

    Contact

    Contact

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