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A softer path to stronger muscles for arthritis?

NCT ID NCT07772687

Symptom relief Sponsor: University of Bonn Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 19, 2026 · Last updated Aug 20, 2026 · Updated 1 time

Summary

This study tests whether blood flow restriction training (BFRT) — using pressure cuffs during low-load exercise — can help people with rheumatoid or psoriatic arthritis build muscle with less joint strain than conventional strength training. Adults with these conditions will be randomly assigned to BFRT, standard resistance training, or no training for 12 weeks. Researchers will measure muscle growth, disease activity, and how well participants stick with the program.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Blood flow restriction training (BFRT) using pressure cuffs during low-load exercise
What this could lead to
If it works, this could offer a gentler way for people with arthritis to build muscle and improve function without stressing painful joints.
What could go wrong
This is a small pilot study, so results may not be definitive. The training may be hard to tolerate, and there are risks like blood clots, though people at higher risk are excluded.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

102 people

The number who actually took part.

Started

Jun 2022

Finished

Jan 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 99 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * diagnosed with rheumatoid arthritis (RA) or psoriatic arthritis (PsA) * none of the exclusion criteria listed below * age 18 years or older * signed informed consent form Exclusion Criteria: * history of deep vein thrombosis or pulmonary artery embolism * current use of blood thinners * peripheral arterial occlusive disease * infection within the last two weeks * angina pectoris * refusal to give informed consent

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Conditions

The condition(s) this trial relates to.

psoriatic arthritis rheumatoid arthritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Psoriatic arthritis Rheumatoid arthritis

Contacts and locations

Locations

  • University Hospital Bonn, Clinic of Internal Medicine III, Department of Oncology, Haematology, Rheumatology and Clinical Immunology

    Bonn, North Rhine-Westphalia, 53127, Germany

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