Blood test may spot brain fog risk after heart surgery

NCT ID NCT04679259

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at whether certain substances in the blood can signal if someone will have memory or thinking problems after heart surgery. Researchers measured levels of D-amino acid oxidase, D-serine, and serine in 82 adults before and after surgery. They also tested thinking skills and checked for confusion. The goal was to see if these blood markers could be early warning signs of cognitive decline.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could lead to a simple blood test to identify patients at risk for cognitive decline after heart surgery, allowing for earlier support.

What could go wrong

This is a small, completed observational study, not a treatment trial. The blood markers may not reliably predict cognitive problems in larger or different groups of patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Postoperative Cognitive Complications

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • SMG-SNU Boramae Medical Center

    Seoul, Select State/Province, 07061, South Korea