Blood test may spot brain fog risk after heart surgery

NCT ID NCT04679259

Completed Diagnosis Sponsor: SMG-SNU Boramae Medical Center Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at whether certain substances in the blood can signal if someone will have memory or thinking problems after heart surgery. Researchers measured levels of D-amino acid oxidase, D-serine, and serine in 82 adults before and after surgery. They also tested thinking skills and checked for confusion. The goal was to see if these blood markers could be early warning signs of cognitive decline.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could lead to a simple blood test to identify patients at risk for cognitive decline after heart surgery, allowing for earlier support.
What could go wrong: This is a small, completed observational study, not a treatment trial. The blood markers may not reliably predict cognitive problems in larger or different groups of patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Postoperative Cognitive Complications

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

POSTOPERATIVE COGNITIVE DYSFUNCTION

Contacts and locations

Locations

SMG-SNU Boramae Medical Center

Seoul, Select State/Province, 07061, South Korea

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