Could a new anesthetic keep your mind sharper after a procedure?

NCT ID NCT07673978

Ongoing Disease control Sponsor: The Second Affiliated Hospital of Chongqing Medical University Source: ClinicalTrials.gov ↗

First seen Jun 29, 2026 · Last updated Jun 30, 2026 · Updated 1 time

Summary

This study compares two sedatives—ciprofol and propofol—used during painless gastroscopy and colonoscopy. The goal is to see which drug leads to less cognitive decline after the procedure. Researchers will also monitor side effects like changes in blood pressure and heart rate. The trial includes adults aged 18–65 with normal cognitive function before the procedure.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: ciprofol
What this could lead to: If ciprofol causes less cognitive decline than propofol, it could become a preferred anesthetic for procedures like endoscopy, especially in older adults.
What could go wrong: This is a single-center Phase 4 study with 298 participants, so results may not apply broadly. Cognitive changes after anesthesia are often temporary and hard to measure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Postoperative Cognitive Complications

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

POSTOPERATIVE COGNITIVE DYSFUNCTION

Contacts and locations

Locations

The Second Affiliated Hospital Of Chongqing Medical University

Chongqing, Chongqing Municipality, 400010, China

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