Leukemia drug shows promise in french compassionate use study

NCT ID NCT03751072

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at how well blinatumomab works and how safe it is in 92 adults with B-cell acute lymphoblastic leukemia that had come back or was not responding to treatment. Patients received the drug through a French compassionate use program. Researchers measured survival, response rates, and side effects to better understand the drug's real-world impact.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
blinatumomab (a drug that helps immune cells attack leukemia cells)
What this could lead to
If results are positive, this could support wider use of blinatumomab for hard-to-treat leukemia patients who have few options.
What could go wrong
This is a retrospective review of a compassionate use program, not a controlled trial. Results may not be as strong as in formal studies, and side effects can be serious.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CABANNES-HAMY Aurélie

    Paris, 75010, France

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