ECMO bleeding mystery: new study probes hidden clotting defects

NCT ID NCT03070912

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at 257 emergency patients on ECMO (a heart-lung machine) to understand why many experience serious bleeding. Researchers measured how often bleeding occurred and checked for defects in von Willebrand factor, a key clotting protein. The goal is to find links between ECMO type and bleeding risk.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could help doctors better predict and manage bleeding in patients on ECMO support.

What could go wrong

This is an observational study, not a treatment trial. It may not lead to direct changes in care, and results may not apply to all ECMO patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Hemorrhage hereditary von Willebrand disease von Willebrand disease (hereditary or acquired)

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CH ARRAS

    Arras, France

  • CH Boulogne

    Boulogne-sur-Mer, France

  • CH DOUAI

    Douai, France

  • CH Dunkerque

    Dunkirk, 59385, France

  • Ch Tourcoing

    Tourcoing, France

  • Ch Valenciennes

    Valenciennes, France

  • Hôpital Cardiologie, CHU

    Lille, France